The Interreg X-BRAIN.net, a cross-border two-year project, has started in collaboration with key project partners, including the Neurology Clinic at SC Cattinara Hospital ASUGI, the Science and Research Centre (ZRS) Koper, and the Department of Neurology at General Hospital Izola. The research findings will be utilized in rehabilitation and preventive initiatives.

Project with it´s full title: ˝Network for cross-border cooperation aimed at the rehabilitation of the post-stroke patient with innovative technologies˝is coordinated by Dr. Gianni Biolo, Professor of Internal Medicine at UniTS and Director of the Medical Clinic at SC ASUGI, in collaboration with Dr. Filippo Di Girolamo (DSM). Three additional project partners are participating in the project: ZRS Koper (under Dr. Rado Pišot's leadership), the Department of Neurology at General Hospital Izola (led by Dr. Radivoj Nardin and Dr. Bojan Rojc), and the Neurology Clinic at SC Cattinara Hospital ASUGI (headed by Dr. Paolo Manganotti).

The project also includes the participation of two associated partners: Ministry of Health of the Republic of Slovenia and the Central Directorate for Health, Social Policy, and Disability of the Autonomous Region of Friuli Venezia Giulia. Both of them have important role to highlight the significance of collaboration among institutions in bilingual border regions.

The X-BRAIN.net project addresses a common health challenge of the Programme Area in relation to the development and improvement of research and innovation capacity and the introduction of new technologies in hospitals in the Programme Area. Post-stroke patients occupy 15% of the capacity of health facilities in the Programme Area. Starting post-stroke rehabilitation as early as possible is crucial. In addition, bilingualism is an important factor and therefore cross-border cooperation between institutions is essential to provide quality health care in a bilingual area.

Dr. Gianni Biolo explains, "The aim of the X-BRAIN.net project is to implement, refine, and exchange bilingual protocols for motor and neurocognitive rehabilitation previously developed in a European intergovernmental cooperation project between Italy and Slovenia, and to devise innovative solutions for rehabilitation services in the cross-border area. These innovative protocols and technologies will be introduced in hospitals on both sides of the border."

The program involves an experimental study examining inactivity among healthy individuals in the age group most prone to strokes. This study seeks to identify the adverse motor, metabolic, and neurocognitive effects of physical inactivity, enabling the development of targeted therapies encompassing physical, dietary, and cognitive exercises.

Dr. Biolo adds, "The outcomes will guide the establishment of 'active rooms' in neurological departments at hospitals in Trieste and Izola. Equipped with cutting-edge technologies, these rooms will facilitate early motor and neurocognitive rehabilitation of stroke patients post clinical stabilization."

Collaborating partners from both countries endeavor to standardize healthcare in bilingual areas through preliminary experimental studies and subsequent application of the findings to patients in both geographical regions.

The kick-off meeting was held at Cattinara Hospital in Trieste, during which the goals, roles, and responsibilities of the partners were defined.

The study's findings will not only directly impact stroke patients in rehabilitation but also provide guidelines to the general population to prevent the negative physical, metabolic, and cognitive consequences of a sedentary lifestyle