A smarter Europe

IMMUNOCLUSTER-2

Introduction of a clinical study with an advanced cellular aHyC at interregional level
Duration
24
months
Start date
September 2023
End date
August 2025
Partner
6
Budget
749.059,60 €
ERDF Budget
599.247,68 €
Progress
30%
 
The project
Project summary

Policy objective: PO1 - A more competitive and smarter Europe by promoting innovative and smart economic transformation and regional ICT connectivity

Specific objective: SO1 - Developing and enhancing research and innovation capacities and the uptake of advanced technologies

Typology: capitalization project

IIMMUNOCLUSTER-2 project addresses the strengthening of cross-border cooperation to improve the quality of life of the population.

Objectives
  • The general goal of the project is the initiation of a clinical trial for the treatment of triple negative breast cancer (TNBC) with a cell-based vaccine (aHyC) at the interregional level, to create the possibility of providing personalized advanced cancer therapies in an accessible and affordable way, to develop and improve innovation capabilities, and enabling the introduction of advanced technologies.
  • Considering the existing situation, the project will promote innovation and improve technology transfer to SMEs, strengthen cooperation between innovative companies, research and healthcare institutions, and allow the capitalization of the results achieved in the previous project INTERREG ITASLO 2014-2020 Immuno-Cluster in a new integrated framework at regional level.
Output

Management and coordination is going according to plan: we organized a kick-off meeting, which took place on September 7, 2023 online. At the meeting, we officially presented the content of the project to the members of all PPs, the planned activities in the project by work groups, information on the coordination of the project implementation and the administrative obligations of the partnership, as well as the time frames for achieving the project results. At the meeting, a steering committee was also appointed, consisting of representatives of all participating PPs, which will take care of the flow of information within PPs, between individual PPs and between PPs and VPs. The first periodic meeting took place live on 26 January 2024 at the Celica premises in Ljubljana. An interview was also published in the local media: https://sis-egiz.eu/2024/01/30/preboji-so-na-pragu/. As part of the activities for the preparation of aHyC immunohybridomas, the partners ZTM, VBC and Celica determined the protocol for the preparation of nDC in the NANT-XL bioreactor and the specifications of the leukapheresis preparation for the isolation of monocytes. We prepared and adapted a protocol for the preparation of aHyC immunohybridomas for TNRD and prepared a clinical study protocol for the treatment of TNBC with aHyC immunohybridomas. We have already submitted an application for a clinical trial to the JAZMP and the National Ethics Commission.

Partner

Celica, biomedicinski center, d.o.o
Onkološki inštitut Ljubljana
VivaBioCell S.p.A
Università degli studi di Udine
Azienda Sanitaria Universitaria Friuli Centrale
Zavod Republike Slovenije za transfuzijsko medicino

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